derail

1. (transitive) To cause to come off the tracks.Examples: "The train was destroyed when it was derailed by the collision."; "Among recommendations arising out of the accident were that greater attention should be devoted to the means of derailing runaways on lines so heavily graded as the Highland main line; were it double throughout, catch points would, of course, be laid in, but the catchpoint problem is a difficult one on a single line."transitive

2. (intransitive) To come off the tracks.Examples: "Fortunately, the CrossCountry train did not derail when it struck the mud. It could easily have been much worse."intransitive

3. (intransitive, figurative) To deviate from the previous course or direction.Examples: "The conversation derailed once James brought up politics."figurativelyintransitive

4. (transitive, figurative) To cause to deviate from a set course or direction.Examples: "The protesting students derailed the professor's lecture."; "Our offices are full of the walking wounded--people who are suicidal, have been hospitalized after the sexual involvement, unable to hold their usual jobs, derailed from intimate relationships, unable to get on with their lives as they once had planned."figurativelytransitive