loric

1. (genetics) A cosmid vector derived from the lambda phage replicon.Examples: "We describe the construction and use of a cosmid vector, loric, which is derived from the phage lambda origin of replication and appears to be more stable than ColE1-derived cosmids. Loric recombinants can be efficiently packaged in vivo to yield 100-300 micrograms of DNA per liter that is linear and has single-stranded cos ends."; "The cosmid vector loric ( 'lambda-origin cosmid' ) is designed to allow rapid mapping of restriction sites in cloned DNAs and thus to facilitate analyses of large regions of chromosomes."; "In order to improve the stability of the recombinant cosmid and increase DNA yield, the ColE replicon was replaced with the lambda phage replicon (Little and Cross, 1985) creating the loric (or 'lambda-origin cosmid') vector."uncountable